The anti-inflammatory and analgesic effects of norvedan a novel, non-steroidal agent.

@article{Davies1976TheAA,
  title={The anti-inflammatory and analgesic effects of norvedan a novel, non-steroidal agent.},
  author={Joanne E Davies and D. N. Kellett and Judith C. Pennington},
  journal={Archives internationales de pharmacodynamie et de therapie},
  year={1976},
  volume={221 2},
  pages={274-82}
}
Norvedan (2-phenyl-4-p-chlorophenyl-thiazole-5-ylacetic acid) has been investigated for anti-inflammatory activity using an 'adjuvant arthirits' in rats and for analgesic activity using a writhing test in mice and a pressure test in rats. At oral doses of 10, 30 and 100 mg/kg Norvedan caused a dose-related inhibition of the primary swelling of the paw injected with adjuvant and the development of secondary lesions was also inhibited. Writhing induced in mice by i.p. administered acetic acid was… CONTINUE READING