The anti-epileptic effect of 3-aminopropylarsonate on electrically-kindled and N-methyl-d-aspartate-kindled amygdala

@article{AbdulGhani1996TheAE,
  title={The anti-epileptic effect of 3-aminopropylarsonate on electrically-kindled and N-methyl-d-aspartate-kindled amygdala},
  author={Abdul-Salam Abdul-Ghani and Philip J. E. Attwell and Henry F. Bradford},
  journal={Brain Research},
  year={1996},
  volume={742},
  pages={305-312}
}
The effects of 3-aminopropylarsonate, an arsono analogue of GABA, was tested on the development of electrically-kindled amygdala and on the expression of generalized seizure activity in electrically and NMDA fully amygdala-kindled rats. Intra-amygdaloid microinjection of 3-aminopropylarsonate (10 nmol in 0.5 microl injection vehicle) inhibited electrical epileptogenesis by keeping the seizure score at or below stage 1 on the Racine scale, and the afterdischarge duration (ADD) at or below 19.70… 
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