The anorectic effects of CRH and restraint stress decrease with repeated exposures.

  title={The anorectic effects of CRH and restraint stress decrease with repeated exposures.},
  author={Dean D Krahn and B A Gosnell and Mark J. Majchrzak},
  journal={Biological psychiatry},
  volume={27 10},
Intracerebroventricular (icv) administration of corticotropin-releasing hormone (CRH) or exposure to a restraint stressor causes acute anorexia in rats. However, the effects on food intake of repeated injections of CRH or repeated exposures to restraint stress have not been previously reported. As the effects of these more chronic CRH and stress treatments may be of greater relevance to emerging hypotheses of the pathogenesis of human eating and affective disorders, we measured the changes in… CONTINUE READING


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Publications referenced by this paper.
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The effects of long - term intracerebroventricular administration of corticotropin - releasing factor on food intake , body weight and hypothalamicpituitaryadrenal hormones ( Abstract 1737 )

  • M Hotta
  • Proc Endocrinol Soc
  • 1989

Effects of central administration of corticotropin - releasing factor ( CRF ) on schedulecontrolled responding and central monoaminergic metabolites in pigeons ( Abstract 7393 )

  • A Lei, ST Ahlers, WojniclO FHE, C Harrod, IE Barrett
  • Fed Proc
  • 1988

Effects of chronic stress on brain and pituitary corticotropin - releasing factor receptors ( Abstract )

  • GJ Kant, SM Anderson, EB DeSouza
  • Soc Neurosci
  • 1988

Effects of cortiooffopinreleasing factor on food intake and brown adipose tissue thermogenesis in rats

  • DR Britton, GF Koob, J Rivier, W Vale
  • Am J Physiol
  • 1988

Corticotropin releasing hormone : Relevance to normal physiology and to the pathophysiology of depression and anorexia nervosa

  • PW Gold, MA Kling, CH Kellner
  • 1987

Neuropeptide function in affective illness : Corticotropin - releasing hormone and somatostatin as model systems

  • PW Gold, DR Rnhinow
  • 1987

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