The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl)glutathione ATPase of human erythrocyte.

@article{Singhal1991TheAC,
  title={The anionic conjugates of bilirubin and bile acids stimulate ATP hydrolysis by S-(dinitrophenyl)glutathione ATPase of human erythrocyte.},
  author={Sharad S Singhal and Rohita Sharma and Sona Gupta and Hassan Ahmad and Piotr Zimniak and Anna Radominska and Roger Lester and Yogesh C. Awasthi},
  journal={FEBS letters},
  year={1991},
  volume={281 1-2},
  pages={255-7}
}
These studies demonstrate that bilirubin-ditaurate (an analog of bilirubin-diglucuronide), lithocholic acid 3-O-sulfate, and lithocholic acid 3-O-glucuronide, which are believed to be transported from liver into bile through an active transport process stimulate ATP hydrolysis by purified dinitrophenylglutathione ATPase of human erythrocytes. The Km and Vmax values of the enzyme for these substrates are similar to those for dinitrophenylglutathione indicating the transport mechanisms for… CONTINUE READING

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