The angiotensin I converting enzyme gene as a susceptibility factor for dementia.

@article{Richard2001TheAI,
  title={The angiotensin I converting enzyme gene as a susceptibility factor for dementia.},
  author={Florence Richard and I Fromentin-David and Fr{\'e}d{\'e}ric Ricolfi and Pierre Ducimeti{\`e}re and Claude Di Menza and Philippe Amouyel and Nicole Helbecque},
  journal={Neurology},
  year={2001},
  volume={56 11},
  pages={1593-5}
}
The frequency of a genetic susceptibility vascular factor, the deletion (D) allele of the angiotensin I converting enzyme gene (ACE), coding for a key enzyme of the renin angiotensin system, was characterized in two independent case--control studies. The results of the current study suggest that bearing at least one ACE D allele is a risk factor to develop dementia for subjects older than 74 years. This observation reinforces the hypothesis of a major implication of vascular risk factors in the… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Association of ACE I/D gene polymorphism with vascular dementia: a meta-analysis.

Hua Liu, Ming Liu, +4 authors Yi Wang
Journal of geriatric psychiatry and neurology • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…