The angiotensin I converting enzyme gene and predisposition to high blood pressure.

@article{Harrap1993TheAI,
  title={The angiotensin I converting enzyme gene and predisposition to high blood pressure.},
  author={Stephen Brian Harrap and H. Rosemarie Davidson and J. Michael Connor and Florent Soubrier and Pierre Corvol and Regina Fraser and Chris J. W. Foy and Graham C. M. Watt},
  journal={Hypertension},
  year={1993},
  volume={21 4},
  pages={455-60}
}
Phenotypic abnormalities of the renin-angiotensin system have been associated with the predisposition to high blood pressure. The angiotensin I converting enzyme (ACE) gene has been implicated as a candidate gene. We examined the distribution of common alleles of the ACE gene and measured circulating components of the renin-angiotensin system and urinary sodium excretion in 170 young Caucasian adults with contrasting genetic predisposition to high blood pressure. Predisposition was defined on… CONTINUE READING

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Genetics and the risk of coronary heart disease.

The Medical journal of Australia • 1992
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Glomerular hyperfiltration and increased plasma renin activity in young adults predisposed to high blood pressure, (abstract

SB Harrap, GCM Watt, DL Davies, R Fraser
Hypertens • 1992

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