The angiotensin I converting enzyme gene and predisposition to high blood pressure.

@article{Harrap1993TheAI,
  title={The angiotensin I converting enzyme gene and predisposition to high blood pressure.},
  author={S. Harrap and H. R. Davidson and J. Connor and F. Soubrier and P. Corvol and R. Fraser and C. Foy and G. Watt},
  journal={Hypertension},
  year={1993},
  volume={21 4},
  pages={
          455-60
        }
}
  • S. Harrap, H. R. Davidson, +5 authors G. Watt
  • Published 1993
  • Medicine
  • Hypertension
  • Phenotypic abnormalities of the renin-angiotensin system have been associated with the predisposition to high blood pressure. The angiotensin I converting enzyme (ACE) gene has been implicated as a candidate gene. We examined the distribution of common alleles of the ACE gene and measured circulating components of the renin-angiotensin system and urinary sodium excretion in 170 young Caucasian adults with contrasting genetic predisposition to high blood pressure. Predisposition was defined on… CONTINUE READING
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