The anemia of chronic disorders: studies of marrow regulation and iron metabolism.

  title={The anemia of chronic disorders: studies of marrow regulation and iron metabolism.},
  author={S W Douglas and John W. Adamson},
  volume={45 1},
Marrow regulation and iron metabolism were evaluated in 17 patients with mild or moderate anemia associated with chronic disorders. In addition, whole blood P50 and red cell 2,3-diphosphoglycerate (DPG) levels were measured. The study group consisted of seven patients with non-hematologic malignancies, nine with infection or inflammation, and one with idiopathic hypoproliferative anemia. The mean whole blood P50 and DPG levels were elevated to 28.5 +/- 1.9 mm Hg and 7.03 +/- 0.83 mumole/ml… 

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