The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors.

@article{Claessens1996TheAP,
  title={The androgen-specific probasin response element 2 interacts differentially with androgen and glucocorticoid receptors.},
  author={Frank Claessens and Philippe Alen and Ann Devos and Ben Peeters and Guido Verhoeven and Wilfried Rombauts},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 32},
  pages={19013-6}
}
The nuclear receptors constitute a large family of transcription factors characterized by a well conserved DNA-binding domain. The receptors for glucocorticoids, progestins, mineralocorticoids, and androgens constitute a subgroup because they bind in vitro with high affinity to DNA elements containing a partial palindrome of the core sequence 5'-TGTTCT-3'. In vivo, however, the corresponding steroids differentially regulate the expression of their target genes, even when more than one receptor… CONTINUE READING