The androgen receptor and genetic susceptibility to ovarian cancer: results from a case series.

@article{Levine2001TheAR,
  title={The androgen receptor and genetic susceptibility to ovarian cancer: results from a case series.},
  author={D A Levine and J Boyd},
  journal={Cancer research},
  year={2001},
  volume={61 3},
  pages={908-11}
}
  • D A Levine, J Boyd
  • Published 2001 in Cancer research
Our objectives were to test whether polymorphic variation in the (CAG)n repeat of the androgen receptor (AR) gene affects penetrance of germ-line BRCA mutations for ovarian cancer or age of diagnosis for ovarian cancer. Using a case-series study design, 179 consecutive Ashkenazi Jewish ovarian cancer patients were genotyped for AR repeat length and BRCA mutation status. There was no association between AR repeat length and presence of a BRCA mutation. However, ovarian cancer patients from both… CONTINUE READING

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3 Excerpts

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