The anatomy of a comprehensive constrained, restrained refinement program for the modern computing environment – Olex2 dissected

  title={The anatomy of a comprehensive constrained, restrained refinement program for the modern computing environment – Olex2 dissected},
  author={Luc J. Bourhis and Oleg V. Dolomanov and Richard J. Gildea and Judith A. K. Howard and Horst Puschmann},
  journal={Acta Crystallographica. Section A, Foundations and Advances},
  pages={59 - 75}
An in-depth presentation is given of olex2.refine, the new refinement engine integrated in the Olex2 program. 

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