The anaphase promoting complex is required for memory function in mice.

@article{Kuczera2011TheAP,
  title={The anaphase promoting complex is required for memory function in mice.},
  author={Tanja Kuczera and R. Stilling and Hung-En Hsia and Sanaz Bahari-Javan and S. Irniger and K. Nasmyth and F. Sananbenesi and A. Fischer},
  journal={Learning & memory},
  year={2011},
  volume={18 1},
  pages={
          49-57
        }
}
  • Tanja Kuczera, R. Stilling, +5 authors A. Fischer
  • Published 2011
  • Psychology, Medicine
  • Learning & memory
  • Learning and memory processes critically involve the orchestrated regulation of de novo protein synthesis. On the other hand it has become clear that regulated protein degradation also plays a major role in neuronal plasticity and learning behavior. One of the key pathways mediating protein degradation is proteosomal protein destruction. The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase that targets proteins for proteosomal degradation by the 26S proteasome. While the… CONTINUE READING
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