The analytical specificity of human chorionic gonadotropin assays determined using WHO International Reference Reagents.

@article{Whittington2010TheAS,
  title={The analytical specificity of human chorionic gonadotropin assays determined using WHO International Reference Reagents.},
  author={Jodell E Whittington and Corinne R. Fantz and Ann M. Gronowski and Christopher R. McCudden and Richard Mullins and Lori Sokoll and Carmen L Wiley and Andy Wilson and David G. Grenache},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2010},
  volume={411 1-2},
  pages={81-5}
}
BACKGROUND Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone with considerable molecular heterogeneity. There is uncertainty regarding which hCG variants are detected by different hCG assays. The analytical specificity of 8 hCG assays was investigated. METHODS WHO International Reference Reagents for hCG, nicked hCG (hCGn), beta subunit (hCGbeta), nicked beta subunit (hCGbetan), and beta core fragment (hCGbetacf) were individually added to hCG-free human serum… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
15 Citations
25 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Human choriogonadotrophin protein core and sugar branchesheterogeneity:basicandclinical insights.HumReprodUpdate2009;15:69–95

  • SF deMedeiros, RJ Norman
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…