The analysis of peak expiratory flow data using a three-level hierarchical model.

@article{Lambert2004TheAO,
  title={The analysis of peak expiratory flow data using a three-level hierarchical model.},
  author={Paul C. Lambert and Paul R. Burton and Keith R. Abrams and Adrian M Brooke},
  journal={Statistics in medicine},
  year={2004},
  volume={23 24},
  pages={3821-39}
}
Peak expiratory flow (PEF) is a measure commonly used in clinical practice and research for respiratory diseases such as asthma. In research, PEF is usually recorded in a diary for a 2-week period with two or more measurements per day. Interest may lie in whether certain groups of individuals tend to have higher or lower PEF. In addition the variability of PEF may be of interest as, for example, asthmatics tend to have more variable airways. In this paper we develop a three-level hierarchical… CONTINUE READING