The analysis of factors affecting the threshold on repeated 18F-FDG-PET/CT investigations measured by the PERCIST protocol in patients with esophageal carcinoma.

@article{Fencl2012TheAO,
  title={The analysis of factors affecting the threshold on repeated 18F-FDG-PET/CT investigations measured by the PERCIST protocol in patients with esophageal carcinoma.},
  author={Pavel Fencl and Otakar Belohl{\'a}vek and T Harustiak and Milada Zemanov{\'a}},
  journal={Nuclear medicine communications},
  year={2012},
  volume={33 11},
  pages={1188-94}
}
BACKGROUND When applying the PET Response Criteria in Solid Tumors protocol, a threshold value based on standardized uptake value corrected to lean body mass (SUL) in liver parenchyma, or in the blood pool, is used: to metabolically specify a measurable lesion; to calculate metabolic tumor volume (mTV) and its product total lesion glycolysis (TLG); and as a limit for response measurement. The problem with using changes in glucose metabolism as a marker for response to therapy is its… CONTINUE READING