The analysis of categorical data from cross-over trials using a latent variable model.

@article{Kenward1991TheAO,
  title={The analysis of categorical data from cross-over trials using a latent variable model.},
  author={Michael G. Kenward and Byron Jones},
  journal={Statistics in medicine},
  year={1991},
  volume={10 10},
  pages={1607-19}
}
A latent variable model for categorical data is described. The nuisance parameters in the model can be eliminated from the analysis through the use of a conditional likelihood and this leads to an analysis based on a log-linear model. It is shown how the structure of a cross-over trial allows considerable simplification in the formulation of this model and routine application of well-known statistical packages. The method is illustrated by data from a three-period cross-over trial on the relief… CONTINUE READING