The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions.

@article{Naef2003TheAE,
  title={The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions.},
  author={Myrtha Naef and Michele Curatolo and Steen Petersen-Felix and Lars Arendt-Nielsen and Alex M. Zbinden and Rudolf Brenneisen},
  journal={Pain},
  year={2003},
  volume={105 1-2},
  pages={79-88}
}
From folk medicine and anecdotal reports it is known that Cannabis may reduce pain. In animal studies it has been shown that delta-9-tetrahydrocannabinol (THC) has antinociceptive effects or potentiates the antinociceptive effect of morphine. The aim of this study was to measure the analgesic effect of THC, morphine, and a THC-morphine combination (THC-morphine) in humans using experimental pain models. THC (20 mg), morphine (30 mg), THC-morphine (20 mg THC+30 mg morphine), or placebo were… CONTINUE READING
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