The anaerobic chytridiomycete fungus Piromyces sp. E2 produces ethanol via pyruvate:formate lyase and an alcohol dehydrogenase E.

@article{Boxma2004TheAC,
  title={The anaerobic chytridiomycete fungus Piromyces sp. E2 produces ethanol via pyruvate:formate lyase and an alcohol dehydrogenase E.},
  author={Brigitte Boxma and Frank Voncken and Sander A. Jannink and Theo A. van Alen and Anna Akhmanova and Susanne W H van Weelden and Jaap J. van Hellemond and Gu{\'e}nola Ricard and Martijn Huynen and Aloysius G. M. Tielens and Johannes H. P. Hackstein},
  journal={Molecular microbiology},
  year={2004},
  volume={51 5},
  pages={1389-99}
}
Anaerobic chytridiomycete fungi possess hydrogenosomes, which generate hydrogen and ATP, but also acetate and formate as end-products of a prokaryotic-type mixed-acid fermentation. Notably, the anaerobic chytrids Piromyces and Neocallimastix use pyruvate:formate lyase (PFL) for the catabolism of pyruvate, which is in marked contrast to the hydrogenosomal metabolism of the anaerobic parabasalian flagellates Trichomonas vaginalis and Tritrichomonas foetus, because these organisms decarboxylate… CONTINUE READING

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