The amylase-creatinine clearance ratio following cardiopulmonary bypass.

@article{Murray1981TheAC,
  title={The amylase-creatinine clearance ratio following cardiopulmonary bypass.},
  author={William R. Murray and Sid Mittra and Debashish Mittra and L. B. Roberts and K. M. Taylor},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1981},
  volume={82 2},
  pages={
          248-53
        }
}
The incidence of unexplained pancreatitis in patients dying after cardiac operations has been recorded as 16%, with evidence to implicate ischemia in the pathogenesis of the pancreatitis. Increased amylase--to--creatinine clearance ratios (ACCR), suggesting pancreatic dysfunction, have been reported in patients following nonpulsatile cardiopulmonary bypass (CPB). Pulsatile CPB is increasingly recognized to be a more physiological form of perfusion, particularly with respect to capillary blood… CONTINUE READING

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