The amplitude of the resting-state fMRI global signal is related to EEG vigilance measures

@article{Wong2013TheAO,
  title={The amplitude of the resting-state fMRI global signal is related to EEG vigilance measures},
  author={Chi Wah Wong and Valur T. Olafsson and Omer Tal and Thomas T. Liu},
  journal={NeuroImage},
  year={2013},
  volume={83},
  pages={983-90}
}
In resting-state functional magnetic resonance imaging (fMRI), functional connectivity measures can be influenced by the presence of a strong global component. A widely used pre-processing method for reducing the contribution of this component is global signal regression, in which a global mean time series signal is projected out of the fMRI time series data prior to the computation of connectivity measures. However, the use of global signal regression is controversial because the method can… CONTINUE READING