The amphiphilic character of glycogenin.

  title={The amphiphilic character of glycogenin.},
  author={Mar{\'i}a Elena Carrizo and Michelle Miozzo and Bruno Maggio and Juan Agust{\'i}n Curtino},
  journal={FEBS letters},
  volume={509 2},
This study describes for the first time the amphiphilicity of the protein moiety of proteoglycogen. Glycogenin but not proteoglycogen associates to phospholipid vesicles and forms by itself stable Gibbs and Langmuir monolayers at the air-buffer interface. The adsorption free energy (-6.7 kcal/mol) and the glycogenin collapse pressure (47 mN/m) are indicative of its high surface activity which can thermodynamically drive and retain the protein at the membrane interface to a maximum equilibrium… CONTINUE READING