The amphetamine-associated context exerts a stronger motivational effect in low-anxiety rats than in high-anxiety rats.

@article{Lehner2017TheAC,
  title={The amphetamine-associated context exerts a stronger motivational effect in low-anxiety rats than in high-anxiety rats.},
  author={Małgorzata H Lehner and Marek Gryz and Aleksandra Wisłowska-Stanek and Danuta Turzyńska and Alicja Sobolewska and Anna Sk{\'o}rzewska and Adam Płaźnik},
  journal={Behavioural brain research},
  year={2017},
  volume={330},
  pages={97-107}
}
This study used the conditioned place preference test to explore the effects of subchronic amphetamine administration on drug-associated cues in rats with different emotional reactivity. We also examined the changes in markers of dopaminergic activity in brain regions in response to the amphetamine-paired context, after a withdrawal period preceded by subchronic amphetamine treatment. We used low-anxiety (LR) and high-anxiety (HR) rats, which are known to exhibit distinct levels of… CONTINUE READING