The aminopropeptide of collagen.

  title={The aminopropeptide of collagen.},
  author={Rupert Timpl and Robert Glanville},
  journal={Clinical orthopaedics and related research},
Aminopropeptides are triple-standard structures with a molecular weight of about 40,000-45,000 located at the amino end of procollagens. They are released during the conversion of procollagen into collagen by specific proteases cleaving a single Pro-Gln peptide bond. The individual peptide chains usually consist of a compact noncollagenous domain stabilized by intrachain disulfide bridges and a collagenous domain folded into a triple helix. Chemical and immunologic analyses of different types… CONTINUE READING