The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

Abstract

While the cellular mechanisms of liver regeneration have been thoroughly studied, the role of extracellular matrix (ECM) in liver regeneration is still poorly understood. We utilized a proteomics-based approach to identify the shifts in ECM composition after CCl4 or DDC treatment and studied their effect on the proliferation of liver cells by combining… (More)
DOI: 10.1038/srep27398

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