The alpha-isoform of caveolin-1 is a marker of vasculogenesis in early lung development.

@article{Ramirez2002TheAO,
  title={The alpha-isoform of caveolin-1 is a marker of vasculogenesis in early lung development.},
  author={Maria I Ramirez and Lee Pollack and Guetchyn Millien and Yu Xia Cao and Aston Alexander Hinds and Miles Coburn Williams},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2002},
  volume={50 1},
  pages={
          33-42
        }
}
Caveolin-1 is a scaffolding protein component of caveolae, membrane invaginations involved in endocytosis, signal transduction, trans- and intracellular trafficking, and protein sorting. In adult lung, caveolae and caveolin-1 are present in alveolar endothelium and Type I epithelial cells but rarely in Type II cells. We have analyzed patterns of caveolin-1 expression during mouse lung development. Two caveolin-1 mRNAs, full-length and a 5' variant that will translate mainly into caveolin-1alpha… CONTINUE READING

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