The alpha/beta ratio for prostate cancer: what is it, really?

@article{Bentzen2005TheAR,
  title={The alpha/beta ratio for prostate cancer: what is it, really?},
  author={S\oren M\oller Bentzen and Mark A. Ritter},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={2005},
  volume={76 1},
  pages={1-3}
}
Two recent studies of fractionated external beam radiotherapy in early prostate cancer provide outcome data that allow a statistical estimation of the alpha/beta-ratio of the linear-quadratic model when combined with clinical data on the steepness of the dose-response curve. Results of the large randomized PR5 trial by the Ontario Clinical Oncology Group/National Cancer Institute of Canada yield an estimate of alpha/beta at 1.12 Gy with 95% confidence interval (-3.3, 5.6) Gy. A non-randomized… CONTINUE READING

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