The allosteric role of the Ca2+ switch in adhesion and elasticity of C-cadherin.

@article{Sotomayor2008TheAR,
  title={The allosteric role of the Ca2+ switch in adhesion and elasticity of C-cadherin.},
  author={Marcos Sotomayor and Klaus Schulten},
  journal={Biophysical journal},
  year={2008},
  volume={94 12},
  pages={4621-33}
}
Modular proteins such as titin, fibronectin, and cadherin are ubiquitous components of living cells. Often involved in signaling and mechanical processes, their architecture is characterized by domains containing a variable number of heterogeneous "repeats" arranged in series, with either flexible or rigid linker regions that determine their elasticity… CONTINUE READING