The allergy epidemic extends beyond the past few decades

@article{Isolauri2004TheAE,
  title={The allergy epidemic extends beyond the past few decades},
  author={Erika Isolauri and Anu Huurre and Seppo Salminen and Olli Impivaara},
  journal={Clinical \& Experimental Allergy},
  year={2004},
  volume={34}
}
Background Increased prevalence of allergic diseases in western societies has been described as an epidemic. The precise turning point for the epidemic and the antigens responsible for it remain obscure. 
View on Wiley
ncbi.nlm.nih.gov
126 Citations
Highly Influential Citations
4
Background Citations
38
Results Citations
2

126 Citations

Early life exposures and development of allergic disease in infants with familial risk: Results from ongoing probiotic intervention trials

A revision of risk determinants of the ongoing allergy epidemic is searched for in order to clarify the role of environmental factors in the development of allergy.

Increasing trend in atopy markers prevalence in a Croatian adult population between 1985 and 1999

A large number of patients with atopy and atopic diseases are diagnosed with atopic Ehlers-Danlos syndrome, and the need for relevant research methods to treat these diseases has been established.

Hay fever, asthma, and eczema and early infectious diseases among children in Kilimanjaro, Tanzania

To investigate the hygiene (or “old friends”) hypothesis in a high‐infectious disease (ID) environment, rural Kilimanjaro, Tanzania, the hypothesis that old friends are good friends is investigated.

Primary versus secondary immunoglobulin E sensitization to soy and wheat in the Multi‐Centre Allergy Study cohort

Background IgE sensitization to soy and wheat is classified as ‘primary’ when generated by food ingestion and ‘secondary’ when it as a consequence of primary sensitization to cross‐reacting pollen…

Is the asthma epidemic still ascending?

Multidisciplinary Approaches to Allergies

"Multidisciplinary Approaches to Allergies" covers diverse aspects ranging from basic molecular mechanisms to societal issues within the framework of multidisciplinary approaches to allergies.

MicroRNA‐21 expression in neonatal blood associated with antenatal immunoglobulin E production and development of allergic rhinitis

  • R.‐F. ChenH.-C. Huang K. D. Yang
  • Medicine, Biology
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2010
This study investigates whether expression of certain microRNAs (miRNAs) in neonatal leucocytes is correlated to IgE production and/or allergic diseases in newborns.

Do patients with skin allergies have higher levels of anxiety than patients with allergic respiratory diseases? Results of a large‐scale cross‐sectional study in a French population

This work states that psychological comorbidity is a known aspect of allergic disease and there is recent evidence that a large proportion of allergic patients remains undiagnosed and untreated for psychological disease.

Food allergy and constipation in childhood: how functional is it?

Understanding the complex mechanisms involved in food allergy could help to improve the management of idiopathic functional constipation in children by addressing the aetiology instead of treating the symptoms.

Asthma prevalence in Nigerian adolescents and adults: systematic review and

This study screened records because studies found not relevant to research question, and excluded records because they were not in line with research question.
...

References

SHOWING 1-10 OF 34 REFERENCES

Hay fever, hygiene, and household size.

A possible explanation forHay fever trends over time is suggested, as well as a recent increase in the prevalence of asthma2 and childhood eczema.

TH2‐polarized immunological memory to inhalant allergens in atopies is established during infaney and early childhood

  • A. YabuharaC. Macaubas P. Holt
  • Medicine, Biology
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1997
This work has shown that T‐cell reactivity to environmental allergens underlying expression of allergic disease in adulthood, develops initially during childhood, and the kinetics of these early responses are poorly known.

Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey

Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany

Probiotics in human disease.

  • E. Isolauri
  • Biology, Medicine
    The American journal of clinical nutrition
  • 2001
Data show that probiotics promote endogenous host defense mechanisms, and modification of gut microflora by probiotic therapy may offer a therapeutic potential in clinical conditions associated with gut-barrier dysfunction and inflammatory response.

Hygiene hypothesis: fact or fiction?

A systematic epidemiologic appraisal of the current hygiene hypothesis evidence can provide a critical analysis of what is currently known and an investigative blueprint for future studies that can ultimately prove causation and improve recommendations, interventions, and therapies.

Increased prevalence of elevated serum IgE and IgG4 antibodies in students over a decade.

Possible explanation for the different trends of asthma and allergy in east and west Germany

  • H. Wichmann
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1996
A clear drifting apart is suggested, suggesting that influences in early childhood are mostly relevant for the initiation of an allergy and that something changed in the west in the 1960s whieh was very important for the development of allergies.

Mode of Delivery and Asthma – Is There a Connection?

It is suggested that caesarean section delivery may be associated with an increased prevalence of atopic asthma.

Possible explanation for the different trends of asthma and allergy in East and West Germany and immigrants

  • A. Kalyoncu
  • Medicine
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 1996
The term 'western lifestyle' includes differences among the communities in factors such as daily salt intake, breast feeding, fish consumption, active and passive smoking, occupational environment, outdoor herbal flora, sick building syndrome, public awareness on asthma and allergy, in addition to the factors listed by the author.