The allergic march in pollinosis: natural history and therapeutic implications.

  title={The allergic march in pollinosis: natural history and therapeutic implications.},
  author={Maurizio Marogna and Paolo Falagiani and Marco Bruno and Alessandro Massolo and Graziella Riva},
  journal={International archives of allergy and immunology},
  volume={135 4},
BACKGROUND That specific immunotherapy (SIT) can slow the march of allergy has been confirmed in controlled clinical trials. However, an assessment of its effects in everyday life, in a large cohort of patients, might provide further useful information. METHODS This observational study comprised 3,643 patients allergic to pollens; 1,620 with pure allergic rhinitis or rhinitis and intermittent or mild-persistent bronchial asthma, responding poorly to standard pharmacological therapy (SPT… CONTINUE READING


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