The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms

@article{LimonSztencel2016TheAF,
  title={The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms},
  author={Anna Limon-Sztencel and Beata S Lipska-Ziętkiewicz and Magdalena Chmara and Bartosz Wasąg and Leszek Bidzan and Beata Renata Godlewska and Janusz Limon},
  journal={Alzheimer's Research & Therapy},
  year={2016},
  volume={8},
  pages={1-7}
}
Over the past two decades, the APOE gene and its polymorphisms have been among the most studied risk factors of Alzheimer disease (AD) development; yet, there are discrepancies between various studies regarding their impact. For this reason, the evaluation of the APOE genotype has not been included in the current European Federation of Neurological Societies guidelines for AD diagnosis and management. This aim of this study was to add to this discussion by assessing the possible influence of… CONTINUE READING