The airway epithelium: soldier in the fight against respiratory viruses.

@article{Vareille2011TheAE,
  title={The airway epithelium: soldier in the fight against respiratory viruses.},
  author={Marjolaine Vareille and Elisabeth Kieninger and Michael J. Edwards and Nicolas Regamey},
  journal={Clinical microbiology reviews},
  year={2011},
  volume={24 1},
  pages={210-29}
}
The airway epithelium acts as a frontline defense against respiratory viruses, not only as a physical barrier and through the mucociliary apparatus but also through its immunological functions. It initiates multiple innate and adaptive immune mechanisms which are crucial for efficient antiviral responses. The interaction between respiratory viruses and airway epithelial cells results in production of antiviral substances, including type I and III interferons, lactoferrin, β-defensins, and… CONTINUE READING