The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?

@article{Bernstein2010TheAE,
  title={The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?},
  author={H Bernstein and Christian Derst and Claudia Stich and Harald Pr{\"u}ss and Daniela Peters and Michael Krauss and Bernhard Bogerts and R{\"u}diger W Veh and Gregor Laube},
  journal={Amino Acids},
  year={2010},
  volume={40},
  pages={453-465}
}
Agmatinase, an ureohydrolase belonging to the arginase family, is widely expressed in mammalian tissues including the brain. Here, it may serve two different functions, the inactivation of the arginine derivative agmatine, a putative neurotransmitter, and the formation of the diamine putrescine. In order to identify the cellular sources of agmatinase expression in the brain, we generated a polyclonal monospecific antibody against recombinant rat agmatinase. With immunocytochemistry, selected… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

The many faces of interferon tau

Amino Acids • 2014
View 7 Excerpts
Highly Influenced

Glia and glial polyamines. Role in brain function in health and disease

Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology • 2016

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Implication of the polyamine system in mental disorders.

Journal of psychiatry & neuroscience : JPN • 2008
View 4 Excerpts
Highly Influenced

Relevance of imidazoline receptors and agmatine to psychiatry: a decade of progress.

Annals of the New York Academy of Sciences • 2003
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…