The ageing pineal gland and its physiological consequences.

  • Robert Reiter
  • Published 1992 in
    BioEssays : news and reviews in molecular…


Melatonin, the chief hormone of the pineal gland, is produced and secreted into the blood in a circadian manner with maximal production always occurring during the dark phase of the light:dark cycle. Whereas the 24h rhythm of melatonin production is very robust in young animals including humans, the cycle deteriorates during ageing. The rhythm of melatonin… (More)


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