The aetiology of B‐cell lymphoid malignancies with a focus on chronic inflammation and infections

  title={The aetiology of B‐cell lymphoid malignancies with a focus on chronic inflammation and infections},
  author={K. E. Smedby and M. Ponzoni},
  journal={Journal of Internal Medicine},
  pages={360 - 370}
  • K. E. Smedby, M. Ponzoni
  • Published 2017
  • Medicine
  • Journal of Internal Medicine
  • B‐cell malignancies are a heterogeneous group of lymphoproliferative disorders with different molecular characteristics and clinical course. It is increasingly recognized that the group displays considerable heterogeneity also regarding aetiologic factors. Here, we summarize the latest developments in the aetiology of B‐cell lymphoid malignancy subtypes focusing on immune perturbation. Severe immune suppression constitutes a strong and well‐established risk factor for aggressive subtypes (e.g… CONTINUE READING
    19 Citations
    Lymphomagenic properties of a HIV p17 variant derived from a splenic marginal zone lymphoma occurred in a HIV‐infected patient
    • 2
    The role of HLA variation in lymphoma aetiology and survival
    • 4
    Clinical management for other iatrogenic immunodeficiency-associated lymphoproliferative disorders
    • 22
    • PDF
    Relevance on the diagnosis of malignant lymphoma of the salivary gland.
    Malaria and risk of lymphoid neoplasms and other cancer: a nationwide population-based cohort study


    Characteristics of diffuse large B cell lymphomas in rheumatoid arthritis.
    • 70
    B-cell non-Hodgkin lymphoma linked to Coxiella burnetii.
    • 50
    • PDF
    Bacteria associated with marginal zone lymphomas.
    • 12
    Primary Cutaneous B-Cell Lymphoma and Borrelia burgdorferi Infection in Patients From the Highlands of Scotland
    • 215