The aetiology of B‐cell lymphoid malignancies with a focus on chronic inflammation and infections

@article{Smedby2017TheAO,
  title={The aetiology of B‐cell lymphoid malignancies with a focus on chronic inflammation and infections},
  author={K. E. Smedby and M. Ponzoni},
  journal={Journal of Internal Medicine},
  year={2017},
  volume={282},
  pages={360 - 370}
}
  • K. E. Smedby, M. Ponzoni
  • Published 2017
  • Medicine
  • Journal of Internal Medicine
  • B‐cell malignancies are a heterogeneous group of lymphoproliferative disorders with different molecular characteristics and clinical course. It is increasingly recognized that the group displays considerable heterogeneity also regarding aetiologic factors. Here, we summarize the latest developments in the aetiology of B‐cell lymphoid malignancy subtypes focusing on immune perturbation. Severe immune suppression constitutes a strong and well‐established risk factor for aggressive subtypes (e.g… CONTINUE READING
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