The advantages of ESI-MS detection in conjunction with HILIC mode separations: Fundamentals and applications.

Abstract

The analysis of highly hydrophilic, ionic, and polar compounds has been performed by HILIC-ESI-MS for the last few years. The use of low aqueous/high polar organic solvent content in HILIC separation mobile phase is almost ideal for ESI-MS detection in many cases, resulting in increased sensitivity. Although the addition of modifiers such as acids or salts… (More)
DOI: 10.1002/jssc.200700630

Cite this paper

@article{Nguyen2008TheAO, title={The advantages of ESI-MS detection in conjunction with HILIC mode separations: Fundamentals and applications.}, author={Hien P. Nguyen and Kevin A Schug}, journal={Journal of separation science}, year={2008}, volume={31 9}, pages={1465-80} }