The advantages and disadvantages of being polyploid

@article{Comai2005TheAA,
  title={The advantages and disadvantages of being polyploid},
  author={Luca Comai},
  journal={Nature Reviews Genetics},
  year={2005},
  volume={6},
  pages={836-846}
}
  • L. Comai
  • Published 1 November 2005
  • Biology
  • Nature Reviews Genetics
Polyploids — organisms that have multiple sets of chromosomes — are common in certain plant and animal taxa, and can be surprisingly stable. The evidence that has emerged from genome analyses also indicates that many other eukaryotic genomes have a polyploid ancestry, suggesting that both humans and most other eukaryotes have either benefited from or endured polyploidy. Studies of polyploids soon after their formation have revealed genetic and epigenetic interactions between redundant genes… 
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References

SHOWING 1-10 OF 177 REFERENCES
Polyploidy and genome evolution in plants.
Novel patterns of gene expression in polyploid plants.
Polyploidy, evolutionary opportunity, and crop adaptation
TLDR
Burgeoning genomic data for both botanical models and major crops offer new avenues for investigation of the molecular and phenotypic consequences of polyploidy, promising new insights into the role of this important process in the evolution of botanical diversity.
Formation of stable epialleles and their paramutation-like interaction in tetraploid Arabidopsis thaliana
TLDR
It is shown that epialleles in tetraploid plants (but not in diploids) interact in trans and lead to heritable gene silencing persisting after segregation from the inactivating allele, which leads to the establishment of functional epigenetic homozygosity and to conversion of new recessive alleles into traits expressed in early polyploid generations.
Evolution by polyploidy and gene regulation in Anura.
TLDR
The high genetic variability of autotetraploid anurans is a result of tetrasomic expression, based on studies of isozymes and other proteins, and Epigenetic mechanisms mediate the reduced expression or silencing of redundant copies of genes in the regulation of gene expression of these tetraploids.
Polyploidy and the evolution of gender dimorphism in plants.
TLDR
It is proposed that polyploidy is a trigger of unrecognized importance for the evolution of gender dimorphism, which operates by disrupting self-incompatibility and leading to inbreeding depression.
The evolutionary dynamics of plant duplicate genes.
Mitotically unstable polyploids in the yeast Pichia guilliermondii
TLDR
Attempts to obtain triploids or tetraploids of P. guilliermondii by sexual hybridization led to mitotically stable hybrids which were in fact aneuploids which obviously suffered drastic chromosome losses immediately after mating.
Aneuploidy and Genetic Variation in the Arabidopsis thaliana Triploid Response
TLDR
It is demonstrated that triploids of A. thaliana are fertile, producing a swarm of different aneuploids, and can readily form tetraploids and function as bridges between euploid types.
...
...