The adsorption of preferential binding peptides to apatite-based materials.

@article{Segvich2009TheAO,
  title={The adsorption of preferential binding peptides to apatite-based materials.},
  author={Sharon J Segvich and Hayes C Smith and David H. Kohn},
  journal={Biomaterials},
  year={2009},
  volume={30 7},
  pages={1287-98}
}
The objective of this work was to identify peptide sequences with high affinity to bone-like mineral (BLM) to provide alternative design methods for functional bone regeneration peptides. Adsorption of preferential binding peptide sequences on four apatite-based substrates [BLM and three sintered apatite disks pressed from powders containing 0% CO(3)(2-) (HA), 5.6% CO(3)(2-) (CA5), 10.5% CO(3)(2-) (CA10)] with varied compositions and morphologies was investigated. A combination of phage display… CONTINUE READING