The adipose tissue renin-angiotensin system and metabolic disorders: a review of molecular mechanisms.

Abstract

The renin-angiotensin system (RAS) is classically known for its role in regulation of blood pressure, fluid and electrolyte balance. In this system, angiotensinogen (Agt), the obligate precursor of all bioactive angiotensin peptides, undergoes two enzymatic cleavages by renin and angiotensin converting enzyme (ACE) to produce angiotensin I (Ang I) and… (More)
DOI: 10.3109/10409238.2012.694843

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