The adipose tissue metabolism: role of testosterone and dehydroepiandrosterone.

@article{Pergola2000TheAT,
  title={The adipose tissue metabolism: role of testosterone and dehydroepiandrosterone.},
  author={Giovanni Pergola},
  journal={International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity},
  year={2000},
  volume={24 Suppl 2},
  pages={
          S59-63
        }
}
  • Giovanni Pergola
  • Published in
    International journal of obesity and related…
    2000
Testosterone (T) and dehydroepiandrosterone (DHEA) are fat-reducing hormones, even though they exert this effect by different mechanisms. In particular, T inhibits lipid uptake and lipoprotein-lipase (LDL) activity in adipocytes, and stimulates lipolysis by increasing the number of lipolytic beta-adrenergic receptors. An indirect sign of these effects is the decrease of adipocyte leptin production. Lastly, T inhibits differentiation of adipocyte precursor cells. Concerning DHEA, this hormone… CONTINUE READING

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