The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non-insulin-dependent) diabetes mellitus.

@article{Lacquemant2004TheAG,
  title={The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non-insulin-dependent) diabetes mellitus.},
  author={Corinne Lacquemant and Philippe Froguel and Stephan Lobbens and Paola Izzo and Christian Dina and Juan Ram{\'o}n Gonz{\'a}lez Ruiz},
  journal={Diabetic medicine : a journal of the British Diabetic Association},
  year={2004},
  volume={21 7},
  pages={776-81}
}
BACKGROUND The ACRP30/adiponectin gene on chromosome 3q27, a region linked to the metabolic syndrome, encodes for the abundant adipocyte-specific secreted protein. Consistent rodent and human studies suggested that this adipokine may be a molecular link between metabolic and cardiovascular diseases. AIMS In order to investigate the role of single nucleotide polymorphisms (SNPs) within the APM1 gene in the susceptibility to coronary artery disease (CAD), we performed a case-control study on… CONTINUE READING

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