The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site.

@article{Morris1991TheAE,
  title={The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site.},
  author={Gilbert F Morris and Michael B. Mathews},
  journal={Journal of virology},
  year={1991},
  volume={65 12},
  pages={6397-406}
}
The transforming region of adenovirus (E1) stimulates expression of a reporter construct linked to the promoter for the human proliferating cell nuclear antigen (PCNA) gene in a cotransfection assay (G. F. Morris and M. B. Mathews, J. Biol. Chem. 264:13856-13864, 1989). The major products of the E1 region were assessed individually for their contribution to transactivation of the PCNA promoter. The E1A 13S and 12S products and the E1B 19-kDa product elevated expression from the PCNA promoter… CONTINUE READING

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