The adenoma-carcinoma sequence applies to epithelial tumours of the papilla of Vater.

@article{Kaiser2002TheAS,
  title={The adenoma-carcinoma sequence applies to epithelial tumours of the papilla of Vater.},
  author={Annette Kaiser and Christian Jurowich and Herbert Sch{\"o}nek{\"a}s and Christoph Gebhardt and Peter Heinz W{\"u}nsch},
  journal={Zeitschrift fur Gastroenterologie},
  year={2002},
  volume={40 11},
  pages={913-20}
}
Adenomas of the papilla of Vater are relatively rare tumours. They are of particular interest, not only because of their particular topography, but also because the adenoma-carcinoma sequence - accepted in the colorectum - has also been postulated to apply to the papilla of Vater. In fact, ampullary adenoma is often considered to be a precancerous lesion. To investigate this hypothesis, we reviewed the surgical specimens obtained during Whipple's procedures carried out to treat histologically… CONTINUE READING