The addition of ribavirin to interferon-alpha therapy in patients with hepatitis C virus-related chronic hepatitis does not modify the thyroid autoantibody pattern but increases the risk of developing hypothyroidism.

Abstract

OBJECTIVE The aim of this study was to investigate whether the addition of ribavirin (RIBA) to interferon-alpha (IFN-alpha) therapy increases the risk of developing thyroid autoimmunity and/or dysfunction. DESIGN AND METHODS The study group (group A) included 72 patients undergoing treatment with IFN-alpha (3-6 million units three times weekly) plus RIBA… (More)

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@article{Carella2002TheAO, title={The addition of ribavirin to interferon-alpha therapy in patients with hepatitis C virus-related chronic hepatitis does not modify the thyroid autoantibody pattern but increases the risk of developing hypothyroidism.}, author={Carlo Carella and Gherardo Mazziotti and Filomena Morisco and Mario Rotondi and Michele Cioffi and Concetta Tuccillo and Francesca Sorvillo and Nicola Caporaso and Giovanni Amato}, journal={European journal of endocrinology}, year={2002}, volume={146 6}, pages={743-9} }