The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma.

@article{Vredenburgh2011TheAO,
  title={The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma.},
  author={James J. Vredenburgh and Annick Desjardins and David A Reardon and Katherine B. Peters and James E. Herndon and Jennifer E. Marcello and John P. Kirkpatrick and John H. Sampson and Leighann Bailey and Stevie Threatt and Allan H. Friedman and Darell D Bigner and Henry S. Friedman},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2011},
  volume={17 12},
  pages={4119-24}
}
PURPOSE To determine if the addition of bevacizumab to radiation therapy and temozolomide, followed by bevacizumab, temozolomide, and irinotecan, for newly diagnosed glioblastoma patients is safe and effective. EXPERIMENTAL DESIGN A total of 75 patients with newly diagnosed glioblastoma were enrolled in the phase II trial that investigated the addition of bevacizumab to standard radiation therapy and daily temozolomide followed by the addition of bevacizumab and irinotecan to adjuvant… CONTINUE READING

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