The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment.

Abstract

AIM Glucocorticoid administration induces insulin resistance (IR) and enhances islet mass and insulin secretion in rodents and humans. Here, we analysed whether these effects are still present after the interruption of dexamethasone treatment. METHODS Adult Wistar rats were distributed into CTL (daily injection of saline for five consecutive days), DEX… (More)
DOI: 10.1111/j.1748-1716.2010.02146.x

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Cite this paper

@article{Rafacho2010TheAC, title={The adaptive compensations in endocrine pancreas from glucocorticoid-treated rats are reversible after the interruption of treatment.}, author={Alex Rafacho and S Quallio and Diego Luis Ribeiro and Sebasti{\~a}o R Taboga and Flavio M. de Paula and A. C. Boschero and Jos{\'e} Roberto Bosqueiro}, journal={Acta physiologica}, year={2010}, volume={200 3}, pages={223-35} }