The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic

@inproceedings{Tirumalai2017TheAO,
  title={The adaptation of Escherichia coli cells grown in simulated microgravity for an extended period is both phenotypic and genomic},
  author={Madhan R Tirumalai and Fathi Karouia and Quyen Ha Tran and Victor G. Stepanov and Rebekah J. Bruce and Christina M Ott and Duane L. Pierson and George E. Fox},
  booktitle={npj Microgravity},
  year={2017}
}
Microorganisms impact spaceflight in a variety of ways. They play a positive role in biological systems, such as waste water treatment but can be problematic through buildups of biofilms that can affect advanced life support. Of special concern is the possibility that during extended missions, the microgravity environment will provide positive selection for undesirable genomic changes. Such changes could affect microbial antibiotic sensitivity and possibly pathogenicity. To evaluate this… CONTINUE READING

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