The acute transcriptional response to resistance exercise: impact of age and contraction mode

@article{Deane2019TheAT,
  title={The acute transcriptional response to resistance exercise: impact of age and contraction mode},
  author={Colleen S. Deane and Ryan M. Ames and B. Phillips and M. Weedon and Craig R. G. Willis and C. Boereboom and H. Abdulla and S. S. Bukhari and J. Lund and John P. Williams and D. Wilkinson and Kenneth Smith and I. Gallagher and F. Kadi and N. Szewczyk and P. Atherton and T. Etheridge},
  journal={Aging (Albany NY)},
  year={2019},
  volume={11},
  pages={2111 - 2126}
}
Optimization of resistance exercise (RE) remains a hotbed of research for muscle building and maintenance. However, the interactions between the contractile components of RE (i.e. concentric (CON) and eccentric (ECC)) and age, are poorly defined. We used transcriptomics to compare age-related molecular responses to acute CON and ECC exercise. Eight young (21±1 y) and eight older (70±1 y) exercise-naïve male volunteers had vastus lateralis biopsies collected at baseline and 5 h post unilateral… Expand
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