The acute regulation of mineralocorticoid biosynthesis: scenarios for the StAR system.

@article{Cherradi1998TheAR,
  title={The acute regulation of mineralocorticoid biosynthesis: scenarios for the StAR system.},
  author={Nadia Cherradi and Alessandro M Capponi},
  journal={Trends in endocrinology and metabolism: TEM},
  year={1998},
  volume={9 10},
  pages={412-8}
}
The zona glomerulosa cell of the adrenal cortex produces mineralocorticoids in response to physiological stimuli (angiotensin II and extracellular K(+)) activating the Ca(2+) messenger system. The mechanisms underlying the generation of the Ca(2+) signal have been analyzed extensively and recent developments have contributed to bridging the gap between intracellular signals and activation of the biological function. This article summarizes the current knowledge on the intracellular targets of… CONTINUE READING