The acute aseptic meningitis syndrome

  title={The acute aseptic meningitis syndrome},
  author={Rodrigo Hasb{\'u}n},
  journal={Current Infectious Disease Reports},
  • R. Hasbún
  • Published 1 August 2000
  • Medicine
  • Current Infectious Disease Reports
The aseptic meningitis syndrome (AMS) is as a diagnostic and management challenge. Since the initial description of AMS in 1925, the differential diagnosis of infectious and noninfectious agents associated with this syndrome has progressed. Although most cases of aseptic meningitis have a benign outcome, several etiologies require urgent therapy if the patient is to survive and be cured. This review will address the differential diagnosis of AMS and focus on recent empiric data that may aid the… 
Acute Aseptic Meningitis Syndrome
This chapter will review the diagnostic and management challenges to some of the most common causes of acute aseptic meningitis syndrome, and briefly discuss herpes viruses, arboviruses, dengue, Zika, chikungunya, syphilis, partially treated bacterialMeningitis, human immunodeficiency virus, and Lyme disease.
Management of Acute Bacterial Meningitis in Children
The epidemiology of ABM in children, indications of cranial imaging, role of different models and serum biomarkers in diagnosing ABM, and management including the use of adjunctive therapies and methods of prevention are presented.
Aseptic Meningitis and Its Viral Etiologies, Clinical Characteristics and Management Practices in Children: A Retrospective Hospital-Based Study From Jordan
Enterovirus is the most common identified cause of paediatric aseptic meningitis in Jordan, and although PCR revealed an identified virus in around half of the patients, nevertheless, there was no adjustment in the management plan regarding duration of empirical antibiotic use and hospital stay.
Complement C7 deficiency presenting as recurrent aseptic meningitis.
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Encephalitis and meningitis (EM) are severe infections of the central nervous system associated with high morbidity and mortality. The etiology of EM in Kazakhstan is not clearly defined, so from
A Metagenomics – Based Diagnostic Approach for Central Nervous System Infections in Hospital Acute Care Setting
It is shown that the analytical sensitivity of mNGS to detect pathogens is comparable to that of PCR in simulated cerebrospinal fluid specimens, which makes this method suitable for application in the acute care hospital setting.
Fatal Meningitis in Swine after Intrathecal Administration of Adeno-associated Virus Expressing Syngeneic Interleukin-10.
A metagenomics-based diagnostic approach for central nervous system infections in hospital acute care setting
A metagenomic next generation sequencing (mNGS)-based approach for broad-range detection of pathogens associated with CNS infections suitable for application in the acute care hospital setting and holds promise to benefit patients with central nervous system infections of unknown etiology.


The acute aseptic meningitis syndrome.
A careful approach to the patient and a rational use of laboratory studies are the basis for establishing a specific diagnosis and assuring a favorable outcome of acute aseptic meningitis.
Aseptic meningitis, a disease of diverse etiology: clinical and etiologic studies on 854 cases.
Excerpt Sporadic cases of infection of the central nervous system, presumably of viral origin, contribute much of the material received by a virus diagnostic laboratory. The present report is conce...
A clinical, epidemiologic and laboratory investigation of aseptic meningitis during the four-year period, 1955-1958. I. Observations concerning etiology and epidemiology.
The relation of some of the newly recognized members of the enterovirus group2 to the aseptic-meningitis syndrome has been established by isolation in tissue culture of viruses from patients with these illnesses.
The triad of neurologic manifestations of Lyme disease
Although sometimes incomplete, the triad of neurologic manifestations of Lyme disease— meningitis, cranial neuritis, and radiculoneuritis—presents a unique clinical picture.
The challenge of drug-induced aseptic meningitis.
A thorough history on prior drug intake must be conducted in every case of meningitis, with special focus on nonsteroidal anti-inflammatory drugs, antibiotics, intravenous immunoglobulins, and OKT3 antibodies (monoclonal antibodies against the T3 receptor) are the most frequent cause of DIAM.
Value of repeat lumbar puncture in the differential diagnosis of meningitis.
When pleocytosis exceeds 1000 cells per cubic millimeter and consists predominantly of polymorphonuclear leukocytes, suspicion of bacterial meningitis is heightened and evaluation of the cerebrospinal fluid at the time of initial examination of the patient is evaluated.
Neurological Manifestations of Infective Endocarditis: A Review
Treatment is based on therapy of the bacterial endocarditis with bactericidal drugs, and therapy of intracerebral lesions with drugs that penetrate the blood-brain barrier, and consideration should be given to surgical intervention in mycotic aneurysms and brain abscesses.
Pitfalls in the recognition of subarachnoid hemorrhage.
Between January 1970 and January 1978, one hundred eighty-two patients were admitted to the University of Iowa Hospitals for treatment of subarachnoid hemorrhages secondary to a ruptured aneurysm.