The acute and subchronic toxicity studies of aqueous leaf and stem bark extract of Costus afer ker (Zingiberaceae) in mice

@article{Udem2009TheAA,
  title={The acute and subchronic toxicity studies of aqueous leaf and stem bark extract of Costus afer ker (Zingiberaceae) in mice},
  author={Samuel Chukwuneke Udem and Chukwunonso Kenechukwu Ezeasor},
  journal={Comparative Clinical Pathology},
  year={2009},
  volume={19},
  pages={75-80}
}
This work investigated the acute and subchronic toxicity profile of aqeous stem bark and leaf extract of Costus afer ker (Zingiberaceae). This plant is used extensively for food, economic, and medicinal purposes in Nigeria. Acute oral toxicity studies in male and female mice did not produce any sign of acute toxicity or death even at the dose of 4,000 mg/kg. Thirty-six albnino Wistar mice of varied sexes weighing between 28 and 35 g were divided into four groups. Groups A, B, and C were given… CONTINUE READING

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