The activity of microcin E492 from Klebsiella pneumoniae is regulated by a microcin antagonist.

Abstract

Microcin E492 is a polypeptide antibiotic that is produced and excreted by Klebsiella pneumoniae. Different growth conditions of the producer strain affect microcin activity. The production of a microcin antagonist is responsible for the changes in microcin activity. The microcin antagonist is induced when cells are iron-deprived, resulting in a low… (More)

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